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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SKP2
All Species:
19.39
Human Site:
S256
Identified Species:
42.67
UniProt:
Q13309
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13309
NP_005974.2
424
47761
S256
Q
T
L
L
S
S
C
S
R
L
D
E
L
N
L
Chimpanzee
Pan troglodytes
XP_001147537
379
42771
E215
S
S
C
S
R
L
D
E
L
N
L
S
W
C
F
Rhesus Macaque
Macaca mulatta
XP_001093834
422
47441
S254
K
T
L
L
S
S
C
S
R
L
D
E
L
N
L
Dog
Lupus familis
XP_546346
749
81658
S581
K
T
L
L
S
S
C
S
R
L
D
E
L
N
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z0Z3
424
47748
S256
A
T
L
L
S
S
C
S
R
L
D
E
L
N
L
Rat
Rattus norvegicus
Q9QZH7
276
30442
A113
D
N
A
L
R
T
F
A
Q
N
C
R
N
I
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001007983
443
49750
S277
E
L
M
L
S
K
C
S
M
L
E
E
L
N
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001036659
499
55071
I311
D
D
D
I
C
A
E
I
A
K
N
E
A
L
E
Honey Bee
Apis mellifera
XP_395497
484
54314
K320
G
L
D
M
E
C
I
K
N
L
M
K
L
K
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780472
456
51238
T269
L
T
L
A
E
H
S
T
A
L
E
V
L
D
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O49286
360
39891
Q197
A
I
G
E
N
C
N
Q
L
Q
S
L
N
L
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.3
91.9
52.3
N.A.
86.3
23.5
N.A.
N.A.
64.1
N.A.
N.A.
N.A.
30
27.8
N.A.
31.3
Protein Similarity:
100
89.3
94.5
54.6
N.A.
92.9
36.7
N.A.
N.A.
74.4
N.A.
N.A.
N.A.
50.9
50.6
N.A.
50
P-Site Identity:
100
0
93.3
93.3
N.A.
93.3
6.6
N.A.
N.A.
60
N.A.
N.A.
N.A.
6.6
13.3
N.A.
33.3
P-Site Similarity:
100
6.6
100
100
N.A.
93.3
26.6
N.A.
N.A.
80
N.A.
N.A.
N.A.
26.6
26.6
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
0
10
10
0
10
0
10
19
0
0
0
10
0
0
% A
% Cys:
0
0
10
0
10
19
46
0
0
0
10
0
0
10
0
% C
% Asp:
19
10
19
0
0
0
10
0
0
0
37
0
0
10
0
% D
% Glu:
10
0
0
10
19
0
10
10
0
0
19
55
0
0
19
% E
% Phe:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% F
% Gly:
10
0
10
0
0
0
0
0
0
0
0
0
0
0
10
% G
% His:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
10
0
0
10
10
0
0
0
0
0
10
0
% I
% Lys:
19
0
0
0
0
10
0
10
0
10
0
10
0
10
0
% K
% Leu:
10
19
46
55
0
10
0
0
19
64
10
10
64
19
55
% L
% Met:
0
0
10
10
0
0
0
0
10
0
10
0
0
0
0
% M
% Asn:
0
10
0
0
10
0
10
0
10
19
10
0
19
46
10
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
10
0
0
0
0
0
0
10
10
10
0
0
0
0
0
% Q
% Arg:
0
0
0
0
19
0
0
0
37
0
0
10
0
0
0
% R
% Ser:
10
10
0
10
46
37
10
46
0
0
10
10
0
0
0
% S
% Thr:
0
46
0
0
0
10
0
10
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _